Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 5/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8022460 | 1.00 | GRIA2 (0.37) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11524939 | 0.88 | GRIA2 (0.45) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11524934 | 0.88 | GRIA2 (0.45) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL8005231 | 0.86 | MAOA (0.43) | HRH3SLC6A2SLC6A4 | |
| SCHEMBL8005228 | 0.86 | MAOA (0.43) | HRH3SLC6A2SLC6A4 | |
| SCHEMBL9450875 | 0.84 | GRIA1 (0.48) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL8030150 | 0.83 | MEN1 (0.44) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL8398865 | 0.83 | MEN1 (0.44) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL8030151 | 0.83 | MEN1 (0.44) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL8031953 | 0.78 | SIGMAR1 (0.37) | GRIA2GRIA1GRIA3HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670322-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5582764-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0670322-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-06 | — | — | EP | disclosed |