Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28489608 | 1.00 | SPHK1 (0.38) | SPHK1LMNACYP2D6GMNNPOLB | |
| SCHEMBL9440860 | 0.82 | TSHR (0.38) | SPHK1LMNATSHRTHRBGPR84 | |
| SCHEMBL6687172 | 0.80 | LMNA (0.40) | SPHK1LMNACYP2D6GMNNPOLB | |
| Bromide SCHEMBL25273190 | 0.75 | TSHR (0.53) | LMNATSHRTHRBALDH1A1HSD17B10 | |
| Bromide SCHEMBL28820475 | 0.75 | TSHR (0.53) | LMNATSHRTHRBALDH1A1HSD17B10 | |
| Bromide SCHEMBL29136397 | 0.75 | TSHR (0.53) | LMNATSHRTHRBALDH1A1HSD17B10 | |
| Bromide SCHEMBL29136393 | 0.75 | TSHR (0.53) | LMNATSHRTHRBALDH1A1HSD17B10 | |
| SCHEMBL15286171 | 0.75 | TSHR (0.40) | SPHK1LMNATSHRTHRBALDH1A1 | |
| Bromide SCHEMBL8082174 | 0.73 | TSHR (0.50) | LMNATSHRTHRBALDH1A1HSD17B10 | |
| Bromide SCHEMBL10866028 | 0.73 | TSHR (0.50) | LMNATSHRTHRBALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136103-A | MICROSTRUCTURE, HEAT RESISTANCE, THIXOTROPY IN ORGANIC LIQUIDS | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-01-23 | — | — | US | disclosed |