Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2811336 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4ERAD51GAA | |
| SCHEMBL5169945 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ERAD51GAA | |
| SCHEMBL29659875 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ERAD51GAA | |
| SCHEMBL2812517 | 0.80 | ALDH1A1 (0.78) | ALDH1A1MAPTKDM4ERAD51GAA | |
| SCHEMBL10738532 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ERAD51GAA | |
| SCHEMBL11522179 | 0.78 | MEN1 (0.48) | ALDH1A1KDM4EHPGDATMKMT2A | |
| SCHEMBL16654481 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4ERAD51GAA | |
| SCHEMBL16654478 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4ERAD51GAA | |
| SCHEMBL8603028 | 0.77 | MAPT (0.78) | ALDH1A1MAPTKDM4ERAD51GAA | |
| SCHEMBL16672098 | 0.76 | KMT2A (0.58) | ALDH1A1MAPTKDM4ERAD51GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160866-A | CROSSLINKERS FOR NATURAL AND SYNTHETIC RUBBERS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-10 | — | — | US | disclosed |