Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526051 | 1.00 | LMNA (0.60) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL22500684 | 0.97 | SMN1; SMN2 (0.58) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL22500995 | 0.95 | LMNA (0.68) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL18965690 | 0.95 | SMN1; SMN2 (0.55) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL22500735 | 0.92 | SMN1; SMN2 (0.67) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3398620 | 0.90 | LMNA (0.52) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3398750 | 0.90 | LMNA (0.52) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3398238 | 0.90 | LMNA (0.52) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL1980081 | 0.90 | TSHR (0.60) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL3856304 | 0.90 | LMNA (0.52) | LMNATSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136103-A | MICROSTRUCTURE, HEAT RESISTANCE, THIXOTROPY IN ORGANIC LIQUIDS | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-01-23 | — | — | US | disclosed |