Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524787 | 0.84 | TSHR (0.43) | TSHRMAPTTDP1MEN1KMT2A | |
| SCHEMBL18815092 | 0.83 | TSHR (0.54) | TSHRMAPTTDP1MEN1KMT2A | |
| SCHEMBL8515801 | 0.80 | MAPT (0.57) | TSHRMAPTTDP1MEN1KMT2A | |
| SCHEMBL11633022 | 0.80 | TSHR (0.51) | TSHRMAPTTDP1MEN1KMT2A | |
| SCHEMBL11326081 | 0.79 | TSHR (0.50) | TSHRMAPTTDP1MEN1KMT2A | |
| SCHEMBL11633347 | 0.79 | TDP1 (0.49) | TSHRMAPTTDP1MEN1KMT2A | |
| SCHEMBL11630340 | 0.79 | TSHR (0.50) | TSHRMAPTTDP1MEN1KMT2A | |
| SCHEMBL11833302 | 0.79 | TSHR (0.50) | TSHRMAPTTDP1MEN1KMT2A | |
| SCHEMBL31647016 | 0.79 | TSHR (0.50) | TSHRMAPTTDP1MEN1KMT2A | |
| SCHEMBL6678642 | 0.78 | MEN1 (0.49) | TSHRMAPTTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136174-A | ANTHELMINICS | E. R. SQUIBB & SONS, INC. (US) | 1979-01-23 | — | — | US | disclosed |