Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27740356 | 0.97 | MAPT (0.55) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| Zinc Chloride SCHEMBL27740353 | 0.94 | MAPT (0.52) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL6678642 | 0.91 | MEN1 (0.49) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL1538922 | 0.88 | MAPT (0.56) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL18815092 | 0.87 | TSHR (0.54) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL11833302 | 0.86 | TSHR (0.50) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL11630094 | 0.85 | TSHR (0.46) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL11752365 | 0.85 | ALDH1A1 (0.49) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL11838661 | 0.82 | MEN1 (0.49) | MAPTTSHRTDP1ALDH1A1MEN1 | |
| SCHEMBL11747845 | 0.82 | MEN1 (0.49) | MAPTTSHRTDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462453-A | Synthesis method and application of propylthio-o-phenylenediamine | 河北美荷药业有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-110498752-B | Preparation method of 4-propylthio-2-nitroaniline | 山东国邦药业有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-112125853-A | Production process and production device of albendazole | 宁夏大漠药业有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-104945292-B | Process for preparing 4-propylthio-o-phenylenediamine | 济南大学 | 2017-04-19 | — | — | CN | claimed |
| CN-104945292-A | Process for preparing 4-propylthio-o-phenylenediamine | UNIV JINAN | 2015-09-30 | — | — | CN | claimed |
| US-20130303782-A1 | PROCESS FOR PREPARATION OF ALBENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2013-11-14 | — | — | US | claimed |
| EP-2643304-A2 | A PROCESS FOR PREPARATION OF ALBENDAZOLE | Sequent Scientific Ltd. (IN) | 2013-10-02 | — | — | EP | claimed |
| WO-2012070069-A2 | A PROCESS FOR PREPARATION OF ALBENDAZOLE | SEQUENT SCIENTIFIC LIMITED (IN) | 2012-05-31 | — | — | WO | claimed |
| CN-101270068-B | Method for preparing 2-nitryl-4-propylthioaniline | CHANGZHOU YABANG QIHUI PHARMACEUTICAL CHEMICAL ENGINEERING CO LTD | 2011-05-18 | — | — | CN | claimed |
| CN-101270091-B | Method for preparing albendazole | CHANGZHOU YABANG QIHUI PHARMACEUTICAL CHEMICAL ENGINEERING CO LTD | 2010-12-29 | — | — | CN | claimed |
| CN-101270068-A | Method for preparing 2-nitryl-4-propylthioaniline | CHANGZHOU YABANG QIHUI PHARMAC (CN) | 2008-09-24 | — | — | CN | claimed |
| CN-101270091-A | Method for preparing albendazole | CHANGZHOU YABANG QIHUI PHARMAC (CN) | 2008-09-24 | — | — | CN | claimed |
| CN-119793522-A | Multilayer core-shell structure catalyst and preparation method and application thereof | 浙江工业大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-119793521-A | Pd with monocrystal4S supported catalyst, preparation method and application | 浙江工业大学 | 2025-04-11 | — | — | CN | disclosed |
| CN-119707831-A | Synthesis of albenzene method for preparing dazole | 河北美荷药业有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119462453-A | Synthesis method and application of propylthio-o-phenylenediamine | 河北美荷药业有限公司 | 2025-02-18 | — | — | CN | disclosed |
| EP-0003951-A1 | Process for the preparation of 2-benzimidazolecarbamic acid esters | ETHYL CORPORATION (US) | 1979-09-19 | — | — | EP | disclosed |
| US-4152522-A | FROM ORTHO-NITROANILINE | ETHYL CORPORATION (US) | 1979-05-01 | — | — | US | disclosed |
| US-4076825-A | Method of treating helminthiasis by parenteral or topical administration of sulfoxide derivatives of benzimidazoles | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |
| US-4072696-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303782-A1 | PROCESS FOR PREPARATION OF ALBENDAZOLE | CPS1, PNPO, NAT1 | MAPT 3557/4885TSHR 2307/4885TDP1 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.