SCHEMBL11526426

SCHEMBL11526426

Cc1cc(C)n(C)c(=O)c1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ATAD2 Q6PL18 1/20 0.41
BRPF1 P55201 1/20 0.39
ALDH1A1 P00352 4/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GLA P06280 2/20 0.35
HPGD P15428 2/20 0.35
CASP1 P29466 2/20 0.35
HSD17B10 Q99714 2/20 0.35
ALOX15 P16050 1/20 0.35
CASP7 P55210 1/20 0.35
POLB P06746 2/20 0.34
USP2 O75604 1/20 0.34
PABPC1 P11940 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
MAPT P10636 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27041738 0.82 ATAD2 (0.41) KDM4EL3MBTL1ATAD2BRPF1ALDH1A1
SCHEMBL4393645 0.76 KDM4E (0.44) KDM4EL3MBTL1ATAD2BRPF1ALDH1A1
Hydrochloric Acid SCHEMBL5487003 0.74 KDM4E (0.43) KDM4EL3MBTL1ATAD2BRPF1ALDH1A1
SCHEMBL31220941 0.74 KDM4E (0.47) KDM4EALDH1A1TDP1HPGDHSD17B10
SCHEMBL21955382 0.73 KDM4E (0.42) KDM4EL3MBTL1ALDH1A1CYP3A4GLA
SCHEMBL21977695 0.73 KDM4E (0.42) KDM4EL3MBTL1ATAD2BRPF1ALDH1A1
SCHEMBL17980826 0.73 KDM4E (0.42) KDM4EL3MBTL1ALDH1A1CYP3A4HPGD
SCHEMBL15647981 0.72 KDM4E (0.39) KDM4EL3MBTL1ATAD2BRPF1ALDH1A1
Hydrochloric Acid SCHEMBL16212688 0.71 KDM4E (0.38) KDM4EL3MBTL1ATAD2BRPF1ALDH1A1
SCHEMBL11636498 0.71 POLB (0.42) KDM4EL3MBTL1BRPF1ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4159202-A PHOTOCOPYING HOECHST AKTIENGESELLSCHAFT (DE) 1979-06-26 US disclosed