Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528518 | 0.75 | ALDH1A1 (0.36) | TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL11526821 | 0.71 | — | — | |
| SCHEMBL2402152 | 0.66 | ALDH1A1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL7901991 | 0.66 | TP53 (0.35) | TSHRMEN1KMT2ALMNA | |
| SCHEMBL8380103 | 0.65 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL29384224 | 0.65 | ALDH1A1 (0.37) | ALDH1A1LMNA | |
| SCHEMBL30531665 | 0.65 | ALDH1A1 (0.37) | ALDH1A1LMNA | |
| SCHEMBL30531670 | 0.65 | ALDH1A1 (0.37) | ALDH1A1LMNA | |
| SCHEMBL11339485 | 0.64 | TDP1 (0.37) | TSHRALDH1A1LMNA | |
| SCHEMBL5029751 | 0.63 | ALDH1A1 (0.36) | TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134770-A | VINYLSULFONYLPROPIONYL COMPOUNDS | MITSUBISHI PAPER MILLS, LTD. (JP) | 1979-01-16 | — | — | US | disclosed |