Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31094048 | 0.98 | KMT2A (0.57) | KMT2ASMN1; SMN2NPC1RAB9AHDAC3 | |
| SCHEMBL32685014 | 0.98 | KMT2A (0.57) | KMT2ASMN1; SMN2NPC1RAB9AHDAC3 | |
| SCHEMBL32684888 | 0.98 | KMT2A (0.57) | KMT2ASMN1; SMN2NPC1RAB9AHDAC3 | |
| SCHEMBL27652865 | 0.97 | KMT2A (0.55) | KMT2ASMN1; SMN2NPC1RAB9AHDAC3 | |
| SCHEMBL28588550 | 0.92 | KMT2A (0.49) | KMT2ASMN1; SMN2NPC1RAB9AHDAC3 | |
| SCHEMBL9016841 | 0.89 | KMT2A (0.57) | KMT2ASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL15987811 | 0.89 | KMT2A (0.57) | KMT2ASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL15549028 | 0.87 | KMT2A (0.68) | KMT2ASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL5696715 | 0.87 | KMT2A (0.68) | KMT2ASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL38661498 | 0.87 | KMT2A (0.68) | KMT2ASMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137200-A | POLYURETHANES | W. R. GRACE & CO. (US) | 1979-01-30 | — | — | US | disclosed |