Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL778630 | 0.95 | POLB (0.54) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL11033524 | 0.90 | ALDH1A1 (0.52) | POLBKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL11526907 | 0.88 | MAPT (0.49) | KMT2AMAPTALDH1A1LMNANPC1 | |
| SCHEMBL780497 | 0.87 | ALDH1A1 (0.50) | KMT2AMAPTALDH1A1LMNANPC1 | |
| Water SCHEMBL11263305 | 0.84 | CSNK2A1 (0.41) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL778475 | 0.83 | POLB (0.62) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL776522 | 0.79 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL10972512 | 0.78 | CSNK2A1 (0.41) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL6056827 | 0.78 | CSNK2A1 (0.55) | POLBKMT2AMEN1GFERALDH1A1 | |
| SCHEMBL10112764 | 0.77 | POLB (0.44) | POLBALDH1A1LMNAHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4170566-A | BLEACHES | FMC CORPORATION (US) | 1979-10-09 | — | — | US | claimed |
| US-4110074-A | Mixed carboxylic/sulfonic anhydrides in peroxygen bleaching | FMC CORPORATION (US) | 1978-08-29 | — | — | US | claimed |
| US-4170566-A | BLEACHES | FMC CORPORATION (US) | 1979-10-09 | — | — | US | disclosed |
| US-4110074-A | Mixed carboxylic/sulfonic anhydrides in peroxygen bleaching | FMC CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |