SCHEMBL11527015

SCHEMBL11527015

CCOP(=S)(Cl)SC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 2/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9245383 0.76 TSHR (0.47) ALDH1A1HSD17B10TSHRTDP1CYP3A4
SCHEMBL11212020 0.74 TSHR (0.45) ALDH1A1HSD17B10TSHRTDP1CYP3A4
SCHEMBL10493511 0.73 TP53 (0.48) ALDH1A1HSD17B10TSHRTDP1TP53
SCHEMBL10902473 0.71
Potassium Ion SCHEMBL10882278 0.71 ALDH1A1 (0.42) ALDH1A1HSD17B10TSHRTDP1CYP3A4
Potassium SCHEMBL11446243 0.71 ALDH1A1 (0.42) ALDH1A1HSD17B10TSHRTDP1CYP3A4
SCHEMBL10668390 0.69 ALDH1A1 (0.30) ALDH1A1HSD17B10TSHR
SCHEMBL11853498 0.68
SCHEMBL3822279 0.68 ALDH1A1 (0.41) ALDH1A1HSD17B10TSHRTDP1TP53
SCHEMBL11525057 0.68 TDP1 (0.37) ALDH1A1HSD17B10TSHRTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4150124-A INSECTICIDES, MITICIDES, FUNGICIDES CELAMERCK GMBH & CO. KG (DE) 1979-04-17 US disclosed