Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380020 | 0.76 | KDM4E (0.35) | CYP1A2ALDH1A1HSD17B10CYP2A6CYP3A4 | |
| SCHEMBL598230 | 0.73 | CYP1A2 (0.65) | CYP1A2ALDH1A1HPGDHSD17B10CYP2A6 | |
| SCHEMBL11629826 | 0.71 | CYP1A2 (0.75) | CYP1A2ALDH1A1HPGDHSD17B10CYP2A6 | |
| SCHEMBL10560099 | 0.71 | CYP1A2 (0.62) | CYP1A2ALDH1A1HPGDHSD17B10CYP2A6 | |
| SCHEMBL29853939 | 0.71 | CYP1A2 (0.75) | CYP1A2ALDH1A1HPGDHSD17B10CYP2A6 | |
| SCHEMBL29845609 | 0.69 | CYP1A2 (0.60) | CYP1A2ALDH1A1HPGDHSD17B10CYP2A6 | |
| SCHEMBL29379845 | 0.69 | CYP1A2 (0.60) | CYP1A2ALDH1A1HPGDHSD17B10CYP2A6 | |
| SCHEMBL597771 | 0.69 | CYP1A2 (0.60) | CYP1A2ALDH1A1HPGDHSD17B10CYP2A6 | |
| SCHEMBL6345832 | 0.69 | CYP1A2 (0.54) | CYP1A2ALDH1A1HPGDHSD17B10CYP2A6 | |
| SCHEMBL11530896 | 0.69 | CHRNB2 (0.47) | CYP1A2CYP2A6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4132750-A | RING OPENING POLYMERIZATION OF NORBORNENE DERIVATIVES | SHOWA DENKO K.K. (JP) | 1979-01-02 | — | — | US | disclosed |
| US-4028482-A | LOW VISCOSITY POLYALKENAMER | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1977-06-07 | — | — | US | disclosed |
| US-3959234-A | CATALYSTS OF ORGANOALUMINUM COMPOUNDS AND A TUNGSTEN OR MOLYBDENUM COMPOUND, RING-OPENING | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-05-25 | — | — | US | disclosed |