Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527145 | 1.00 | GRIA1 (0.49) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL24471099 | 0.89 | GRIA2 (0.50) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11524748 | 0.88 | GRIA2 (0.47) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11524743 | 0.88 | GRIA2 (0.47) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11525277 | 0.85 | GRIA1 (0.45) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL11525272 | 0.85 | GRIA1 (0.45) | GRIA1GRIA2GRIA3HRH3USP30 | |
| SCHEMBL2758516 | 0.85 | CYP2A6 (0.50) | GRIA1GRIA2GRIA3HRH3GRIA4 | |
| SCHEMBL8737419 | 0.85 | CYP2A6 (0.50) | GRIA1GRIA2GRIA3HRH3GRIA4 | |
| SCHEMBL26205757 | 0.85 | CYP2A6 (0.50) | GRIA1GRIA2GRIA3HRH3GRIA4 | |
| SCHEMBL11617318 | 0.84 | NPSR1 (0.39) | GRIA1GRIA2GRIA3NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |