Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.46 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.46 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.46 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5991790 | 0.86 | MAPT (0.49) | CNR1CNR2TRPA1LMNAALDH1A1 | |
| SCHEMBL11527226 | 0.86 | CNR2 (0.54) | CNR1CNR2TRPA1LMNAALDH1A1 | |
| SCHEMBL30070803 | 0.85 | HNF4A (0.54) | TRPA1LMNAALDH1A1KLKB1CTSB | |
| SCHEMBL4521629 | 0.85 | HNF4A (0.54) | TRPA1LMNAALDH1A1KLKB1CTSB | |
| SCHEMBL30070764 | 0.83 | CSNK2A1 (0.62) | SRD5A2CNR1CNR2LMNAALDH1A1 | |
| SCHEMBL9856867 | 0.82 | SRD5A2 (0.51) | SRD5A2CNR1CNR2LMNAALDH1A1 | |
| SCHEMBL5990019 | 0.82 | SRD5A2 (0.52) | SRD5A2CNR1CNR2TRPA1KLKB1 | |
| SCHEMBL9816965 | 0.81 | CSNK2A1 (0.64) | TRPA1LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL11513240 | 0.80 | SRD5A2 (0.46) | SRD5A2CNR1CNR2LMNAALDH1A1 | |
| SCHEMBL48194 | 0.79 | CNR2 (0.57) | CNR1CNR2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141995-A | Ketone derivatives | LILLY INDUSTRIES LIMITED (GB) | 1979-02-27 | — | — | US | disclosed |