Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531142 | 0.79 | TP53 (0.42) | TSHRPOLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11528640 | 0.77 | THRB (0.47) | MAPK1TSHRPOLBKMT2AMEN1 | |
| SCHEMBL28474528 | 0.76 | MAPK1 (0.55) | MAPK1TSHRESR2POLBKMT2A | |
| SCHEMBL6630555 | 0.74 | — | — | |
| SCHEMBL757449 | 0.74 | — | — | |
| SCHEMBL701960 | 0.73 | HSD17B10 (0.59) | MAPK1TSHRESR2POLBKMT2A | |
| SCHEMBL1164338 | 0.72 | — | — | |
| SCHEMBL8585126 | 0.72 | MAPK1 (0.52) | MAPK1TSHRESR2POLBKMT2A | |
| SCHEMBL8929843 | 0.72 | — | — | |
| SCHEMBL302524 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145366-A | ACID CATALYST | TEIJIN LIMITED (JP) | 1979-03-20 | — | — | US | claimed |
| US-4145366-A | ACID CATALYST | TEIJIN LIMITED (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4100180-A | PLATINUM OXIDE CATALYST | TEIJIN, LIMITED (JP) | 1978-07-11 | — | — | US | disclosed |