Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5486609 | 1.00 | CA4 (0.42) | CA4CA1FAHD1 | |
| Potassium Ion SCHEMBL29684679 | 0.97 | CA4 (0.44) | CA4CA1FAHD1 | |
| SCHEMBL31656550 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL285039 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL31492942 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL8089675 | 0.94 | CA4 (0.47) | CA4CA1FAHD1 | |
| SCHEMBL4934869 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL11525049 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL285040 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL4934880 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145558-A | Ester derivatives of ether polycarboxylic acids | LEVER BROTHERS COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4133960-A | Novel ester derivatives of ether polycarboxylic acids and process for making same | LEVER BROTHERS COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4058554-A | Novel ester derivatives of ether polycarboxylic acids and process for making same | LEVER BROTHERS COMPANY (US) | 1977-11-15 | — | — | US | disclosed |