Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4934880 | 1.00 | CA4 (0.42) | CA4CA1FAHD1 | |
| Potassium Ion SCHEMBL29684679 | 0.97 | CA4 (0.44) | CA4CA1FAHD1 | |
| SCHEMBL31492942 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL11525049 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| Lithium Ion SCHEMBL31389434 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL5486609 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL285039 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL285040 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL11527646 | 0.94 | CA4 (0.42) | CA4CA1FAHD1 | |
| SCHEMBL8089675 | 0.94 | CA4 (0.47) | CA4CA1FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004344-A1 | Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use | ADITECH PHARMA AB (SE) | 2008-01-03 | — | — | US | disclosed |
| EP-1812374-A1 | NOVEL SALTS OF FUMARIC ACID MONOALKYLESTERS AND THEIR PHARMACEUTICAL USE | Aditech Pharma AB (SE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006050730-A1 | NOVEL SALTS OF FUMARIC ACID MONOALKYLESTERS AND THEIR PHARMACEUTICAL USE | ADITECH PHARMA AB (SE) | 2006-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004344-A1 | Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use | FAH, FH, SLC16A7 | CA4 395/4885CA1 931/4885FAHD1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.