Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9336446 | 0.79 | TSHR (0.34) | CTSAACHETSHR | |
| SCHEMBL525985 | 0.78 | CTSA (0.48) | CTSAACHEKDM4EALDH1A1POLB | |
| SCHEMBL9336350 | 0.78 | TSHR (0.38) | CTSAACHETSHR | |
| SCHEMBL3776800 | 0.77 | CTSA (0.39) | CTSAACHEKDM4EALDH1A1POLB | |
| SCHEMBL9336319 | 0.76 | CTSA (0.31) | CTSAACHE | |
| SCHEMBL9472438 | 0.75 | TSHR (0.40) | CTSAACHETSHR | |
| SCHEMBL11526835 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL8345805 | 0.75 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL11514172 | 0.74 | CTSA (0.43) | CTSAACHEKDM4EALDH1A1POLB | |
| SCHEMBL11515008 | 0.74 | CTSA (0.43) | CTSAACHEKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151229-A | Process for the manufacture of aminoalkyl-phosponic acid esters | CIBA-GEIGY CORPORATION (US) | 1979-04-24 | — | — | US | disclosed |