Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9666727 | 0.81 | EPHX1 (0.57) | EPHX1MMP2MMP1ACHEPOLB | |
| SCHEMBL11529423 | 0.81 | ALDH1A1 (0.32) | MMP2MMP1KMT2A | |
| SCHEMBL19741476 | 0.80 | EPHX1 (0.64) | EPHX1HTT | |
| SCHEMBL5454992 | 0.77 | EPHX1 (0.60) | EPHX1HTT | |
| SCHEMBL6287631 | 0.77 | EPHX1 (0.68) | EPHX1MMP2MMP1ACHE | |
| SCHEMBL6290290 | 0.77 | EPHX1 (0.68) | EPHX1MMP2MMP1ACHE | |
| SCHEMBL11519629 | 0.76 | EPHX1 (0.52) | EPHX1MMP2MMP1ACHEPOLB | |
| SCHEMBL6009312 | 0.75 | EPHX1 (0.59) | EPHX1MMP2MMP1ACHEPOLB | |
| SCHEMBL6289712 | 0.75 | EPHX1 (0.72) | EPHX1MMP2MMP1ACHE | |
| SCHEMBL320112 | 0.73 | EPHX1 (0.85) | EPHX1MMP2MMP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171325-A | Chemical process | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-10-16 | — | — | US | disclosed |