Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16570813 | 0.83 | KDM4E (1.00) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| SCHEMBL429276 | 0.83 | KDM4E (1.00) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| SCHEMBL21436218 | 0.83 | KDM4E (0.67) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| SCHEMBL7122152 | 0.81 | L3MBTL1 (0.48) | KDM4ESMN1; SMN2TSHRALDH1A1GAA | |
| SCHEMBL11205570 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL2674609 | 0.81 | KDM4E (0.95) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL16571085 | 0.81 | KDM4E (0.95) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| SCHEMBL13833218 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL8859868 | 0.81 | KDM4E (0.95) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| Water SCHEMBL7425166 | 0.81 | KDM4E (0.95) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179557-A | Acylation of 7-aminocephalosporanic acids | PRESIDENT OF OSAKA UNIVERSITY (JP) | 1979-12-18 | — | — | US | disclosed |
| US-4123611-A | N-protected amino compounds | PRESIDENT OF OSAKA UNIVERSITY (JP) | 1978-10-31 | — | — | US | disclosed |