SCHEMBL11528372

SCHEMBL11528372

CCCCc1[nH]cnc1CCNC(=N)NC(N)=O

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
XDH P47989 4/20 0.37
EPHX1 P07099 1/20 0.31
HRH2 P25021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11523245 0.96 XDH (0.36) XDHEPHX1HRH2
SCHEMBL11525635 0.95 XDH (0.36) XDHEPHX1
SCHEMBL11527227 0.95 XDH (0.36) XDHEPHX1
SCHEMBL11523042 0.95 XDH (0.36) XDHEPHX1
SCHEMBL11522698 0.94 XDH (0.36) XDHEPHX1HRH2
SCHEMBL11526828 0.94 XDH (0.32) XDH
SCHEMBL11524957 0.91 XDH (0.36) XDHEPHX1HRH2
SCHEMBL11525284 0.90 XDH (0.36) XDHEPHX1HRH2
SCHEMBL11526556 0.90 XDH (0.36) XDHEPHX1HRH2
SCHEMBL11523503 0.90 XDH (0.36) XDHEPHX1HRH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4166860-A TREATMENT OF ACHLORHYDRIA AND DYSMENORRHEA WILLIAM H. RORER, INC. (US) 1979-09-04 US disclosed