Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528812 | 0.79 | POLB (0.43) | — | |
| SCHEMBL11525942 | 0.77 | POLB (0.41) | — | |
| SCHEMBL11677031 | 0.73 | NPC1 (0.32) | MAPTALDH1A1 | |
| SCHEMBL965286 | 0.71 | KMT2A (0.82) | KMT2AHTTALDH1A1MAPK1 | |
| SCHEMBL8535996 | 0.71 | — | — | |
| SCHEMBL11674140 | 0.71 | — | — | |
| SCHEMBL11675174 | 0.70 | — | — | |
| SCHEMBL966438 | 0.70 | KMT2A (0.78) | KMT2AHTTALDH1A1MAPK1 | |
| SCHEMBL17273858 | 0.70 | KMT2A (0.78) | KMT2AHTTALDH1A1MAPK1 | |
| SCHEMBL4803949 | 0.70 | KMT2A (0.78) | KMT2AHTTALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |