Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525942 | 0.98 | POLB (0.41) | POLB | |
| SCHEMBL11528447 | 0.79 | KMT2A (0.48) | — | |
| SCHEMBL8535996 | 0.76 | — | — | |
| SCHEMBL11675174 | 0.74 | — | — | |
| SCHEMBL11676144 | 0.73 | ALOX15 (0.31) | — | |
| SCHEMBL7133796 | 0.71 | — | — | |
| SCHEMBL11529506 | 0.71 | POLB (0.39) | POLB | |
| SCHEMBL11677031 | 0.70 | NPC1 (0.32) | POLB | |
| SCHEMBL27494066 | 0.69 | — | — | |
| SCHEMBL12013049 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |