SCHEMBL11528463

SCHEMBL11528463

O=C(CBr)OCCOCCO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
CYP2C19 P33261 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
TSHR P16473 6/20 0.46
MAPK1 P28482 2/20 0.46
ALDH1A1 P00352 6/20 0.44
TRPA1 O75762 2/20 0.44
TP53 P04637 2/20 0.37
HIF1A Q16665 2/20 0.37
HSD17B10 Q99714 2/20 0.37
EPHX2 P34913 1/20 0.36
THRB P10828 1/20 0.35
HTT P42858 1/20 0.35
MAPT P10636 1/20 0.35
FAAH O00519 1/20 0.32
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31
USP2 O75604 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14273796 0.91 CYP2C19 (0.56) MEN1KMT2ACYP2C19L3MBTL1TSHR
SCHEMBL15616858 0.91 CYP2C19 (0.56) MEN1KMT2ACYP2C19L3MBTL1TSHR
SCHEMBL1887294 0.85
Ethylene Glycol SCHEMBL11213499 0.85 CYP2C19 (0.56) CYP2C19L3MBTL1TSHRALDH1A1TRPA1
SCHEMBL1434603 0.83 CYP2C19 (0.64) CYP2C19L3MBTL1TSHRALDH1A1TRPA1
SCHEMBL6560315 0.81 MEN1 (0.55) MEN1KMT2ACYP2C19TSHRMAPK1
SCHEMBL21876951 0.81 MEN1 (0.55) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL20913720 0.81 MEN1 (0.55) MEN1KMT2ACYP2C19TSHRMAPK1
SCHEMBL3796133 0.81 MEN1 (0.55) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL21055107 0.81 MEN1 (0.55) MEN1KMT2ATSHRMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4153806-A Recovery of vicinal glycol esters by plural stage distillation HALCON RESEARCH AND DEVELOPMENT CORP. (US) 1979-05-08 US disclosed