Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16772 | 0.87 | TSHR (0.61) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL1269088 | 0.87 | TSHR (0.61) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL27697658 | 0.86 | TSHR (0.47) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL16250357 | 0.85 | CYP3A4 (0.51) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| Charcoal, Activated SCHEMBL11214727 | 0.85 | TSHR (0.59) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| Methane SCHEMBL28153878 | 0.85 | TSHR (0.59) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL31757145 | 0.85 | TSHR (0.59) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL8638932 | 0.84 | ALDH1A1 (0.40) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| SCHEMBL8433034 | 0.84 | ALDH1A1 (0.40) | TSHRCYP3A4ATMTDP1ALDH1A1 | |
| Ether SCHEMBL18091197 | 0.84 | TSHR (0.55) | TSHRCYP3A4ATMTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026145-A1 | OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2024-01-25 | — | — | US | disclosed |
| US-20240026145-A1 | OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2024-01-25 | — | — | US | disclosed |
| EP-4206797-A1 | OPHTHALMIC LENS | Menicon Co., Ltd. (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-20210163650-A1 | POLYMER MATERIAL | MENICON CO., LTD. (JP) | 2021-06-03 | — | — | US | disclosed |
| EP-3822296-A1 | POLYMER MATERIAL | Menicon Co., Ltd. (JP) | 2021-05-19 | — | — | EP | disclosed |
| US-4148967-A | Metallized plastic molded product and method for producing same | MITSUBISHI RAYON CO., LTD. (JP) | 1979-04-10 | — | — | US | disclosed |