Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 9/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11521227 | 0.92 | MAPK1 (0.32) | HRH4HRH3 | |
| SCHEMBL11036952 | 0.84 | HRH2 (0.30) | HRH4HRH3HRH2 | |
| SCHEMBL11525577 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL11040900 | 0.82 | — | — | |
| SCHEMBL11398314 | 0.81 | HRH4 (0.55) | HRH4HRH3HRH2 | |
| SCHEMBL11361281 | 0.80 | CYP3A4 (0.41) | HRH2 | |
| SCHEMBL11006984 | 0.80 | HRH4 (0.53) | HRH4HRH3HRH2 | |
| SCHEMBL11006990 | 0.80 | HRH4 (0.53) | HRH4HRH3HRH2 | |
| SCHEMBL2791864 | 0.78 | MEN1 (0.34) | — | |
| SCHEMBL11525286 | 0.77 | HRH2 (0.32) | HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166860-A | TREATMENT OF ACHLORHYDRIA AND DYSMENORRHEA | WILLIAM H. RORER, INC. (US) | 1979-09-04 | — | — | US | disclosed |