Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11451055 | 0.84 | LMNA (0.48) | HSD17B10CYP1A2CYP2C9ALOX15ALOX12 | |
| SCHEMBL11491180 | 0.84 | LMNA (0.48) | HSD17B10CYP1A2CYP2C9ALOX15ALOX12 | |
| SCHEMBL29449283 | 0.81 | LMNA (0.45) | CYP1A2LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL6395202 | 0.78 | BLM (0.57) | HSD17B10CYP2C9CYP2C19HIF1ALMNA | |
| SCHEMBL6395199 | 0.78 | BLM (0.57) | HSD17B10CYP2C9CYP2C19HIF1ALMNA | |
| SCHEMBL6395193 | 0.78 | BLM (0.57) | HSD17B10CYP2C9CYP2C19HIF1ALMNA | |
| SCHEMBL1573246 | 0.77 | LMNA (0.50) | LMNAMAPK1TSHRALDH1A1BLM | |
| SCHEMBL1573247 | 0.77 | LMNA (0.50) | LMNAMAPK1TSHRALDH1A1BLM | |
| SCHEMBL2346696 | 0.77 | LMNA (0.50) | SMN1; SMN2LMNAMAPK1TSHRALDH1A1 | |
| SCHEMBL2346690 | 0.77 | LMNA (0.50) | SMN1; SMN2LMNAMAPK1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163759-A | Process for preparing aromatic hydroxyaldehydes | HAARMANN & REIMER GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-08-07 | — | — | US | disclosed |