Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11440334 | 0.96 | MAPT (0.56) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL6901942 | 0.84 | MAPT (0.67) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11522596 | 0.83 | MAPT (0.65) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL572409 | 0.80 | MAPT (0.61) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11524157 | 0.80 | MAPT (0.60) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11432496 | 0.79 | MAPT (0.59) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11869694 | 0.79 | MAPT (0.59) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11440333 | 0.78 | ALDH1A1 (0.45) | MAPTTDP1L3MBTL1ALDH1A1HCAR3 | |
| SCHEMBL11528773 | 0.77 | ALDH1A1 (0.60) | MAPTTDP1L3MBTL1ALDH1A1GAA | |
| SCHEMBL9501892 | 0.76 | MAPT (1.00) | MAPTTDP1L3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136117-A | PREPARATION OF 2,6-DINITROANILINES | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |