SCHEMBL11528941

SCHEMBL11528941

c1ccc(CC(c2nnn[nH]2)c2nnn[nH]2)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.42
SLC6A2 P23975 3/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
EPHX1 P07099 1/20 0.40
TAAR1 Q96RJ0 4/20 0.38
SIGMAR1 Q99720 2/20 0.38
MAOA P21397 1/20 0.38
CYP2A6 P11509 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
CPA3 P15088 1/20 0.36
FOLH1 Q04609 1/20 0.36
SLC18A2 Q05940 1/20 0.35
ANPEP P15144 1/20 0.35
CYP2D6 P10635 1/20 0.35
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9531756 0.91 SLC6A2 (0.50) CYP1A2SLC6A2SLC6A4SLC6A3EPHX1
SCHEMBL19354261 0.85 IDO1 (0.43) CYP1A2EPHX1CPA3FOLH1IDO1
SCHEMBL19354535 0.85 IDO1 (0.43) CYP1A2EPHX1CPA3FOLH1IDO1
SCHEMBL7448082 0.84 SLC6A2 (0.40) CYP1A2SLC6A2SLC6A4SLC6A3EPHX1
SCHEMBL6785583 0.83 CYP1A2 (0.54) CYP1A2SLC6A2SLC6A4SLC6A3EPHX1
SCHEMBL2093344 0.83 CYP1A2 (0.39) CYP1A2SLC6A2SLC6A4SLC6A3EPHX1
SCHEMBL7507014 0.83 CYP1A2 (0.54) CYP1A2SLC6A2SLC6A4SLC6A3EPHX1
Hydrochloric Acid SCHEMBL6791172 0.82 CYP1A2 (0.53) CYP1A2SLC6A2SLC6A4SLC6A3EPHX1
SCHEMBL5641607 0.80 CYP1A2 (0.41) CYP1A2SLC6A2SLC6A4SLC6A3EPHX1
SCHEMBL7438313 0.80 SLC6A2 (0.40) CYP1A2SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4142029-A Bis-tetrazoles as chemical blowing agents for foaming thermoplastic resins CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed