Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | CPA3 | P15088 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19354261 | 1.00 | IDO1 (0.43) | IDO1CYP1A2KDM4EL3MBTL1TRPA1 | |
| SCHEMBL11528941 | 0.85 | CYP1A2 (0.42) | IDO1CYP1A2CPA3FOLH1EPHX1 | |
| SCHEMBL6000698 | 0.83 | FAAH (0.41) | TRPA1 | |
| SCHEMBL19354511 | 0.82 | SLC6A4 (0.41) | IDO1CYP1A2L3MBTL1 | |
| SCHEMBL19354586 | 0.82 | SLC6A4 (0.41) | IDO1CYP1A2L3MBTL1 | |
| SCHEMBL22885976 | 0.82 | CYP1A2 (0.42) | CYP1A2EPHX1ALPIPKMPTGS1 | |
| SCHEMBL6002903 | 0.82 | FAAH (0.46) | TRPA1 | |
| SCHEMBL19354510 | 0.80 | HTR2A (0.45) | CYP1A2 | |
| SCHEMBL19354584 | 0.80 | HTR2A (0.45) | CYP1A2 | |
| SCHEMBL6002777 | 0.80 | FAAH (0.48) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765064-B1 | Alpha-hydroxy-beta-azido-tetrazoles | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-09-19 | — | — | US | disclosed |
| US-20170260171-A1 | ALPHA-HYDROXY-BETA-AZIDO-TETRAZOLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260171-A1 | ALPHA-HYDROXY-BETA-AZIDO-TETRAZOLES | CYP8B1, HSD3B1, HSD17B1 | IDO1 1816/4885CYP1A2 43/4885KDM4E 2351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.