SCHEMBL11528951

SCHEMBL11528951

Cl[Si](Cl)(Cl)C1C2C=CC(C2)C1[Si](Cl)(Cl)Cl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11527760 0.84
SCHEMBL11527787 0.82
SCHEMBL12749772 0.63
SCHEMBL3180845 0.62
SCHEMBL29393789 0.61 KDM4E (0.38)
SCHEMBL6240119 0.60 ALDH1A1 (0.36) CYP3A4MAPT
SCHEMBL720298 0.60 ALDH1A1 (0.36) CYP3A4MAPT
SCHEMBL17423839 0.60 CYP3A4 (0.33) CYP3A4MAPT
SCHEMBL6847275 0.58
SCHEMBL5010012 0.56 CYP3A4 (0.31) CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4153765-A Curable composition containing EPM or EPDM interpolymers COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1979-05-08 US disclosed
US-4028483-A EPDM interpolymers formed with unsaturated organosilanes COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1977-06-07 US disclosed