Cyclopentanone

Cyclopentanone

SCHEMBL11529014

O=C1CCCC1.O=C1CCCC1.S

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.91
TRIM33 Q9UPN9 2/20 0.91
ALDH1A1 P00352 1/20 0.83
CRBN Q96SW2 2/20 0.35
CA1 P00915 2/20 0.35
CA9 Q16790 1/20 0.35
FKBP5 Q13451 1/20 0.35
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
ESR2 Q92731 1/20 0.31
CDC25B P30305 1/20 0.30
KMT2A Q03164 1/20 0.30
OR51E2 Q9H255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopentanone SCHEMBL27539020 1.00
Cyclohexanone SCHEMBL28744985 0.96 TRIM24 (0.92) TRIM24TRIM33ALDH1A1CRBNCA1
Cyclohexanone SCHEMBL21598036 0.96
Cyclopentanone SCHEMBL1332555 0.95
Cyclopentanone SCHEMBL2797344 0.95 TRIM24 (1.00) TRIM24TRIM33ALDH1A1CRBNCA1
SCHEMBL1262325 0.95 TRIM24 (1.00) TRIM24TRIM33ALDH1A1CRBNCA1
Cyclopentanone SCHEMBL27612284 0.95
Cyclopentanone SCHEMBL57700 0.95
Cyclopentanone SCHEMBL19364 0.95
Cyclohexanone SCHEMBL11544988 0.92 TRIM24 (0.85) TRIM24TRIM33ALDH1A1CRBNCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4163106-A Prostaglandin precursors and processes for preparing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1979-07-31 US claimed
US-4163758-A 2-Nitroethylcyclopentane compounds and process for preparing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1979-08-07 US disclosed
US-4163106-A Prostaglandin precursors and processes for preparing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1979-07-31 US disclosed
US-4073799-A Process for producing 3-formylcyclopentanone derivatives (ZAIDANHOJIN) SAGAMI CHEMICAL RESEARCH CENTER (JA) 1978-02-14 US disclosed