⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopentanone SCHEMBL1332555 | 1.00 | — | — | |
| Cyclopentanone SCHEMBL27612284 | 1.00 | — | — | |
| SCHEMBL1262325 | 1.00 | TRIM24 (1.00) | — | |
| Cyclopentanone SCHEMBL2797344 | 1.00 | TRIM24 (1.00) | — | |
| Cyclopentanone SCHEMBL19364 | 1.00 | — | — | |
| SCHEMBL25380098 | 0.95 | TRIM24 (1.00) | — | |
| Cyclopentanone SCHEMBL3109551 | 0.95 | — | — | |
| Cyclopentanone SCHEMBL11529014 | 0.95 | TRIM24 (0.91) | — | |
| Cyclopentanone SCHEMBL3693524 | 0.95 | — | — | |
| SCHEMBL112034 | 0.95 | TRIM24 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093396-A | Pyridine ether compound containing pyrimidinamine and preparation method and application thereof | 湖南化工研究院有限公司 | 2022-09-23 | — | — | CN | claimed |
| CN-113754639-A | Pyridylether compound containing pyrimidinamine and preparation and application thereof | 湖南化工研究院有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-113754637-A | Pyridine ether compound containing pyrimidinamine | 湖南化工研究院有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-115093396-B | Pyridinylether compound containing pyrimidamine and preparation method and application thereof | 湖南化工研究院有限公司 | 2024-03-29 | — | — | CN | disclosed |
| US-11844822-B2 | Solid formulation and method for preventing or reducing coloration thereof | ELOBIX AB (SE) | 2023-12-19 | — | — | US | disclosed |
| US-20230330176-A1 | PHARMACEUTICAL COMBINATION COMPRISING AN IBAT INHIBITOR AND A BILE ACID BINDER | ALBIREO AB (SE) | 2023-10-19 | — | — | US | disclosed |
| US-11732006-B2 | IBAT inhibitors for the treatment of liver diseases | ALBIREO AB (SE) | 2023-08-22 | — | — | US | disclosed |
| US-20230165974-A1 | COMPOSITIONS AND METHODS FOR DELIVERING PHARMACEUTICALLY ACTIVE AGENTS | MEDIMMUNE, LLC | 2023-06-01 | — | — | US | disclosed |
| US-20230109432-A1 | IBAT INHIBITORS FOR THE TREATMENT OF LIVER DISEASES | ALBIREO AB (SE) | 2023-04-06 | — | — | US | disclosed |
| EP-4143205-A1 | COMPOSITIONS AND METHODS FOR DELIVERING PHARMACEUTICALLY ACTIVE AGENTS | Medimmune, LLC (US) | 2023-03-08 | — | — | EP | disclosed |
| CN-115461357-A | Compositions and methods for delivering pharmaceutically active agents | 免疫医疗有限责任公司 | 2022-12-09 | — | — | CN | disclosed |
| CN-1416425-A | 1,5-bemzothiazepines and their use as hypolipidaemics | ASTRAZENECA AB (SE) | 2003-05-07 | — | — | CN | disclosed |
| WO-2003022830-A1 | BENZOTHIEPINE ILEAL BILE ACID TRANSPORT INHIBITORS | ASTRAZENECA AB (SE) | 2003-03-20 | — | — | WO | disclosed |
| WO-2003022286-A1 | BENZOTHIAZEPINE AND BENZOTHIADIAZEPINE DERIVATIVES WITH ILEAL BILE ACID TRANSPORT (IBAT) INHIBITORY ACTIVITY FOR THE TREATMENT HYPERLIPIDAEMIA | ASTRAZENECA AB (SE) | 2003-03-20 | — | — | WO | disclosed |
| WO-2003022825-A1 | BENZOTHIAZEPINE DERIVATIVES FOR THE TREATMENT OF HYPERLIPIDEMIA | ASTRAZENECA AB (SE) | 2003-03-20 | — | — | WO | disclosed |
| WO-2003020710-A1 | BENZOTHIAZEPINE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-03-13 | — | — | WO | disclosed |
| EP-1263747-A1 | 1,5-BENZOTHIAZEPINES AND THEIR USE AS HYPOLIPIDAEMICS | AstraZeneca AB (SE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2002051806-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2002-07-04 | — | — | WO | disclosed |
| WO-2002050051-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |
| WO-2001066533-A1 | 1,5-BENZOTHIAZEPINES AND THEIR USE AS HYPOLIPIDAEMICS | ASTRAZENECA AB (SE) | 2001-09-13 | — | — | WO | disclosed |