Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.63 |
| ▸ | ZDHHC2 | Q9UIJ5 | 3/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529276 | 1.00 | ZDHHC20 (0.63) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| SCHEMBL11529036 | 0.98 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| SCHEMBL11529044 | 0.98 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| SCHEMBL11530895 | 0.98 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| SCHEMBL11527605 | 0.98 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| SCHEMBL11527610 | 0.98 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| SCHEMBL11529911 | 0.98 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| SCHEMBL11530889 | 0.98 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| SCHEMBL11529918 | 0.98 | ZDHHC20 (0.66) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C | |
| SCHEMBL1831126 | 0.94 | ZDHHC20 (0.56) | ZDHHC20ZDHHC2EPHX1HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154707-A | VINYLENEDICARBONYL COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-05-15 | — | — | US | disclosed |