Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31635506 | 0.85 | CYP2C19 (0.46) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL31635505 | 0.85 | CYP2C19 (0.46) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL2018036 | 0.85 | CYP2C19 (0.46) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL16267418 | 0.83 | NAAA (0.43) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL31635496 | 0.80 | NAAA (0.40) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL11754227 | 0.79 | CYP2C19 (0.41) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL27013612 | 0.78 | EPHX2 (0.43) | CYP2C19NAAAEPHX1HTTCYP19A1 | |
| SCHEMBL1255753 | 0.76 | APOBEC3A (0.35) | CYP2C19NAAAHTTCYP19A1SMN1; SMN2 | |
| SCHEMBL1395028 | 0.75 | — | — | |
| SCHEMBL5014635 | 0.74 | EPHX1 (0.44) | CYP2C19NAAAEPHX1HTTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158654-A | IMPACT STRENGTH, GOOD SURFACE FINISH | PHILLIPS PETROLEUM COMPANY (US) | 1979-06-19 | — | — | US | disclosed |