Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11529364 | 0.99 | THRA (0.48) | THRATHRBHTR1DHTR1BMCHR1 | |
| SCHEMBL11533264 | 0.96 | THRA (0.51) | THRATHRBHTR1BMCHR1PLA2G2A | |
| Hydrochloric Acid SCHEMBL11525645 | 0.95 | THRA (0.50) | THRATHRBHTR1BMCHR1PLA2G2A | |
| SCHEMBL11529387 | 0.93 | HTR1D (0.43) | THRATHRBHTR1DHTR1BMCHR1 | |
| SCHEMBL11529638 | 0.93 | CHRM2 (0.46) | THRATHRBMCHR1CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL11529362 | 0.92 | HTR1D (0.42) | THRATHRBHTR1DHTR1BMCHR1 | |
| Hydrochloric Acid SCHEMBL11528326 | 0.92 | CHRM2 (0.46) | THRATHRBMCHR1CHRM2CHRM4 | |
| SCHEMBL11530074 | 0.92 | THRA (0.47) | THRATHRBMCHR1CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL11533368 | 0.91 | THRA (0.47) | THRATHRBMCHR1CHRM2CHRM4 | |
| SCHEMBL11533262 | 0.89 | THRA (0.43) | THRATHRBHTR1DHTR1BMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140770-A | Benzoylethers and processes for their production | A. NATTERMANN & CIE. GMBH (DE) | 1979-02-20 | — | — | US | disclosed |