Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.61 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15021452 | 0.87 | MAPT (0.63) | MAPTAKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL11528981 | 0.86 | HCAR3 (0.76) | MAPTAKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL11514669 | 0.86 | MAPT (0.60) | MAPTAKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL12089421 | 0.86 | HCAR3 (0.75) | MAPTAKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL23675257 | 0.86 | MAPT (0.61) | MAPTAKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL13063908 | 0.86 | MAPT (0.61) | MAPTAKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL8233274 | 0.86 | MAPT (0.61) | MAPTAKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL2642063 | 0.83 | MAPT (0.51) | MAPTAKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL29703156 | 0.82 | MAPT (0.66) | MAPTAKR1C3AKR1C2AKR1C4AKR1C1 | |
| SCHEMBL25351608 | 0.82 | MAPT (0.66) | MAPTAKR1C3AKR1C2AKR1C4AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150152083-A1 | Compounds and Compositions for Modulating EGFR Activity | IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) | 2015-06-04 | — | — | US | disclosed |
| US-20150152083-A1 | Compounds and Compositions for Modulating EGFR Activity | IRM LLC, A DELAWARE LIMITED LIABILITY COMPANY (BM) | 2015-06-04 | — | — | US | disclosed |
| US-4145342-A | NITRO-DIPHENYLAMINO-AZO-PHENYL DYESTUFFS CONTAINING A POLYALKYENEOXY GROUP | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152083-A1 | Compounds and Compositions for Modulating EGFR Activity | EGFR, ERBB2, ERBB3 | MAPT 2924/4885AKR1C3 4247/4885AKR1C2 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.