Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533473 | 0.95 | CES1 (0.42) | CES1CES2KMT2AMEN1L3MBTL1 | |
| SCHEMBL11534465 | 0.89 | CES1 (0.47) | CES1CES2KMT2AMAPTCYP2C19 | |
| SCHEMBL11532022 | 0.85 | KMT2A (0.40) | CES1CES2KMT2AMEN1HTT | |
| SCHEMBL11531704 | 0.82 | KMT2A (0.38) | CES1CES2KMT2AMEN1MAPT | |
| SCHEMBL11532194 | 0.81 | BCL2 (0.39) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL11530455 | 0.79 | BCL2 (0.37) | KMT2AMEN1MAPTHTTL3MBTL1 | |
| SCHEMBL11531469 | 0.77 | SMN1; SMN2 (0.47) | CES1CES2KMT2AMEN1MAPT | |
| SCHEMBL11533371 | 0.77 | SMN1; SMN2 (0.38) | CES1KMT2AMAPTCYP2C9CYP2C19 | |
| SCHEMBL11532826 | 0.76 | SMN1; SMN2 (0.46) | CES1CES2KMT2AMEN1MAPT | |
| SCHEMBL11535983 | 0.75 | MEN1 (0.41) | KMT2AMEN1CYP2C9CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |