Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533841 | 0.92 | CYP2C9 (0.42) | SMN1; SMN2KMT2AMAPTCYP2C9LMNA | |
| SCHEMBL11532022 | 0.91 | KMT2A (0.40) | KMT2AKDM4ECES1POLBLMNA | |
| SCHEMBL11535581 | 0.84 | OPRM1 (0.44) | SMN1; SMN2PKMKMT2AMAPTCYP2C19 | |
| SCHEMBL11534465 | 0.84 | CES1 (0.47) | SMN1; SMN2PKMKMT2AMAPTCYP2C19 | |
| SCHEMBL11532465 | 0.82 | MAPT (0.39) | SMN1; SMN2PKMKMT2AMAPTCYP2C19 | |
| SCHEMBL11883684 | 0.80 | CYP11B1 (0.57) | SMN1; SMN2KMT2AMAPTCYP2C19KCNN4 | |
| SCHEMBL11532194 | 0.77 | BCL2 (0.39) | KMT2A | |
| SCHEMBL11534461 | 0.76 | CYP2C9 (0.40) | SMN1; SMN2KMT2AMAPTKDM4EPOLB | |
| SCHEMBL11533473 | 0.76 | CES1 (0.42) | SMN1; SMN2KMT2ACES1POLBLMNA | |
| SCHEMBL11530455 | 0.75 | BCL2 (0.37) | SMN1; SMN2KMT2AMAPTKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140782-A | Combating fungi and nematodes with diphenyl-triazolyl-methanes | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |