Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.76 |
| ▸ | HRH1 | P35367 | 1/20 | 0.76 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11531362 | 0.91 | CHRM1 (0.62) | CHRM1HRH1PAK1 | |
| SCHEMBL11632479 | 0.87 | CHRM1 (0.71) | CHRM1HRH1PAK1 | |
| SCHEMBL11666986 | 0.87 | CHRM1 (0.57) | CHRM1HRH1PAK1 | |
| SCHEMBL11529615 | 0.87 | CHRM1 (0.57) | CHRM1HRH1PAK1 | |
| SCHEMBL11527692 | 0.86 | CHRM1 (0.57) | CHRM1HRH1PAK1 | |
| SCHEMBL11531661 | 0.86 | CHRM1 (0.56) | CHRM1HRH1PAK1 | |
| SCHEMBL11533730 | 0.86 | CHRM1 (0.71) | CHRM1HRH1PAK1 | |
| SCHEMBL11479839 | 0.86 | CHRM1 (0.76) | CHRM1HRH1PAK1 | |
| SCHEMBL11536340 | 0.86 | CHRM1 (0.56) | CHRM1HRH1PAK1 | |
| SCHEMBL11529616 | 0.86 | CHRM1 (0.55) | CHRM1HRH1PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172831-A | CENTRAL NERVOUS SYSTEM | LILLY INDUSTRIES LIMITED (GB) | 1979-10-30 | — | — | US | disclosed |
| US-4115568-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-4115574-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-4087421-A | NEUROLEPTIC, ANTI-DEPRESSANT AND ANALGESTIC ACTIVITY | AMERICAN CYANAMID COMPANY (US) | 1978-05-02 | — | — | US | disclosed |