Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12158744 | 0.89 | TSHR (0.57) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL9225409 | 0.89 | TSHR (0.57) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL11871072 | 0.86 | SMN1; SMN2 (0.58) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL11373953 | 0.85 | HAO1 (0.50) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL2739301 | 0.84 | MAPT (0.63) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL4559589 | 0.82 | SMN1; SMN2 (0.61) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL11763415 | 0.81 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| Metbufen SCHEMBL2111106 | 0.81 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL5959979 | 0.79 | MAPT (0.74) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL8537118 | 0.78 | PTPN1 (0.66) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4149413-A | THERMOCHROMIC | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHER IRELAND (GB) | 1979-04-17 | — | — | US | disclosed |