Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459655 | 0.77 | CTNNB1 (0.61) | CES1MAPK1MAPTTDP1CYP3A4 | |
| SCHEMBL11529954 | 0.77 | PTPN1 (0.49) | CES1MAPK1MAPTTDP1CYP3A4 | |
| SCHEMBL2161616 | 0.75 | HIF1A (0.50) | CES1MAPK1MAPTTDP1CYP3A4 | |
| SCHEMBL5695380 | 0.75 | CES1 (0.45) | CES1MAPK1MAPTTDP1CYP3A4 | |
| SCHEMBL7088571 | 0.74 | CTNNB1 (0.54) | CES1MAPK1MAPTTDP1CYP3A4 | |
| SCHEMBL4910963 | 0.74 | CES1 (0.44) | CES1MAPK1MAPTTDP1CYP3A4 | |
| SCHEMBL2049968 | 0.74 | CES1 (0.44) | CES1MAPK1MAPTTDP1CYP3A4 | |
| Formaldehyde SCHEMBL28986972 | 0.73 | CES1 (0.52) | CES1MAPTTDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL27890954 | 0.72 | CES1 (0.52) | CES1MAPK1MAPTTDP1CYP3A4 | |
| SCHEMBL9244395 | 0.72 | CTNNB1 (0.53) | CES1MAPK1MAPTTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4142029-A | Bis-tetrazoles as chemical blowing agents for foaming thermoplastic resins | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |