Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | CES1 | P23141 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28879634 | 0.82 | PTPN1 (0.50) | PTPN1CES1ALDH1A1TSHRHTT | |
| SCHEMBL12816020 | 0.80 | CES1 (0.52) | PTPN1CES1ALDH1A1TSHRHTT | |
| SCHEMBL11536474 | 0.77 | NR4A2 (0.47) | PTPN1CES1ALDH1A1TSHRHTT | |
| SCHEMBL4910963 | 0.77 | CES1 (0.44) | PTPN1CES1ALDH1A1TSHRHTT | |
| SCHEMBL3266513 | 0.77 | PTPN1 (0.50) | PTPN1CES1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL11531333 | 0.77 | CES1 (0.52) | PTPN1CES1ALDH1A1TSHRMAPK1 | |
| SCHEMBL27528437 | 0.74 | CES1 (0.50) | PTPN1CES1ALDH1A1TSHRMAPK1 | |
| SCHEMBL27770792 | 0.72 | TSHR (0.51) | CES1ALDH1A1TSHRHTTKDM4E | |
| SCHEMBL1666976 | 0.72 | CES1 (0.61) | CES1ALDH1A1TSHRCYP3A4MAPT | |
| SCHEMBL15519395 | 0.72 | CES1 (0.56) | CES1ALDH1A1TSHRCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4142029-A | Bis-tetrazoles as chemical blowing agents for foaming thermoplastic resins | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |