Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 8/20 | 0.47 |
| ▸ | CTRC | Q99895 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ATIC | P31939 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.40 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343279 | 0.85 | MPL (0.48) | MPLCTRCCYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL8650449 | 0.80 | MPL (0.52) | MPLCTRCCYP1A2ALDH1A1HIF1A | |
| SCHEMBL31398447 | 0.79 | CYP2D6 (0.56) | MPLCTRCCYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL219389 | 0.79 | CYP2D6 (0.56) | MPLCTRCCYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL3836872 | 0.78 | CYP2D6 (0.54) | MPLCTRCCYP2D6CYP1A2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL30108950 | 0.78 | CYP2D6 (0.54) | MPLCTRCCYP2D6CYP1A2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28226082 | 0.78 | CYP2D6 (0.54) | MPLCTRCCYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL1247911 | 0.78 | CYP2D6 (0.54) | MPLCTRCCYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL14813073 | 0.78 | CYP2D6 (0.54) | MPLCTRCCYP2D6CYP1A2ALDH1A1 | |
| SCHEMBL28935034 | 0.78 | CYP2D6 (0.54) | MPLCTRCCYP2D6CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141890-A | FIBER-REACTIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | claimed |
| US-4092308-A | 4-Sulphomethyl substituted hydroxypyridone azo dyestuffs | CIBA-GEIGY CORPORATION (US) | 1978-05-30 | — | — | US | claimed |
| US-3971738-A | Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | claimed |