Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 8/20 | 0.52 |
| ▸ | CTRC | Q99895 | 2/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.44 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.44 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.44 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11653446 | 0.84 | CTRB1 (0.56) | MPLCTRCCTRB1SENP2SENP1 | |
| SCHEMBL11650539 | 0.84 | CTRB1 (0.56) | MPLCTRCCTRB1SENP2SENP1 | |
| SCHEMBL11532003 | 0.80 | MPL (0.47) | MPLCTRCCTRB1SENP2SENP1 | |
| SCHEMBL943732 | 0.79 | MPL (0.76) | MPLCTRCCTRB1SENP7CYP1A2 | |
| SCHEMBL11883457 | 0.79 | THRB (0.59) | MPLCTRCCTRB1SENP2SENP1 | |
| SCHEMBL5489756 | 0.78 | CYP1A2 (0.64) | MPLCTRCCTRB1SENP2SENP1 | |
| SCHEMBL11232465 | 0.77 | CTRB1 (0.48) | MPLCTRCCTRB1SENP2SENP1 | |
| SCHEMBL2785876 | 0.76 | CTRB1 (0.53) | MPLCTRCCTRB1CYP1A2HIF1A | |
| SCHEMBL29972292 | 0.76 | CTRB1 (0.53) | MPLCTRCCTRB1CYP1A2HIF1A | |
| SCHEMBL41541 | 0.76 | CYP2D6 (0.53) | MPLCTRCCTRB1SENP2SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432542-B1 | Azo dyestuffs and intermediates for their preparation | BAYER AG (DE) | 1994-09-14 | — | — | EP | claimed |
| US-5278293-A | Aromatic amide-alkylenesulfonic acid fiber-reactive dyes | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | claimed |
| EP-0432542-A2 | Azo dyestuffs and intermediates for their preparation | BAYER AG (DE) | 1991-06-19 | — | — | EP | claimed |
| US-4874848-A | FOR DYEING WOOL, LEATHER, POLYAMIDES BLACK OR BROWN | CIBA-GEIGY CORPORATION (US) | 1989-10-17 | — | — | US | claimed |
| EP-0150676-B1 | 1:2 CHROMIUM COMPLEX DYES | CIBA-GEIGY AG (CH) | 1988-10-12 | — | — | EP | claimed |
| US-4661587-A | Bis 1:2 chromium complexes of disazo and azo or azomethine dyes | CIBA-GEIGY CORPORATION (US) | 1987-04-28 | — | — | US | claimed |
| US-4652631-A | LEATHER, WOOL, POLYAMIDES | CIBA-GEIGY CORPORATION (US) | 1987-03-24 | — | — | US | claimed |
| US-4650859-A | WOOL,POLYAMIDES, LEATHER | CIBA-GEIGY CORPORATION (US) | 1987-03-17 | — | — | US | claimed |
| EP-0100297-B1 | BIS-1:2-CHROMIUM COMPLEXES OF DISAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1986-01-08 | — | — | EP | claimed |
| EP-0150676-A2 | 1:2 Chromium complex dyes | CIBA-GEIGY AG (CH) | 1985-08-07 | — | — | EP | claimed |
| EP-0082117-B1 | CHROMIUM COMPLEXES OF POLYAZO DYESTUFFS | CIBA-GEIGY AG (CH) | 1985-04-10 | — | — | EP | claimed |
| US-4502860-A | WOOL, POLYAMIDES, LEATHER | CIBA-GEIGY CORPORATION (US) | 1985-03-05 | — | — | US | claimed |
| EP-0100297-A1 | Bis-1:2-chromium complexes of disazo dyestuffs, their preparation and their use | CIBA-GEIGY AG (CH) | 1984-02-08 | — | — | EP | claimed |
| EP-0082117-A1 | Chromium complexes of polyazo dyestuffs | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | claimed |
| US-4311641-A | Chromium complexes of mixed azo compounds | CIBA-GEIGY CORPORATION (US) | 1982-01-19 | — | — | US | claimed |
| US-4039523-A | YELLOW | CIBA-GEIGY AG (CH) | 1977-08-02 | — | — | US | claimed |
| JP-3024167-A | — | — | None | — | — | JP | disclosed |
| CN-102388064-A | Compositions and methods for screening and using compounds antagonizing spore-surface interactions | GOJO IND INC | 2012-03-21 | — | — | CN | disclosed |
| EP-0005207-A2 | Bis-1:2 chrome-disazo-bisazo methine dyestuffs, their preparation and use for dyeing of leather | CIBA-GEIGY AG (CH) | 1979-11-14 | — | — | EP | disclosed |
| US-4039523-A | YELLOW | CIBA-GEIGY AG (CH) | 1977-08-02 | — | — | US | disclosed |