Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.30 |
| ▸ | KLK7 | P49862 | 1/20 | 0.30 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221475 | 0.88 | CYP2C9 (0.36) | POLBCYP2C9ATML3MBTL1ADORA2A | |
| SCHEMBL11535963 | 0.81 | CYP2C9 (0.35) | POLBCYP2C9 | |
| SCHEMBL11527222 | 0.79 | APP (0.37) | POLBATML3MBTL1ADORA2AADORA2B | |
| SCHEMBL11526282 | 0.76 | L3MBTL1 (0.39) | POLBATML3MBTL1KMT2AMEN1 | |
| SCHEMBL5929177 | 0.69 | GAA (0.44) | POLBATML3MBTL1 | |
| SCHEMBL1911789 | 0.68 | CYP2C9 (0.65) | POLBCYP2C9L3MBTL1ADORA2AADORA2B | |
| SCHEMBL13123104 | 0.68 | CYP2C9 (0.65) | POLBCYP2C9L3MBTL1ADORA2AADORA2B | |
| SCHEMBL28620916 | 0.68 | CYP2C9 (0.65) | POLBCYP2C9L3MBTL1ADORA2AADORA2B | |
| SCHEMBL11526285 | 0.66 | ATM (0.35) | ATML3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL18655709 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |