Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533237 | 1.00 | HTR2C (0.59) | HTR2CCHRM1ALOX15GAACHRNB2 | |
| SCHEMBL30802401 | 0.84 | HTR2C (0.52) | HTR2CCHRM1LMNATSHRALDH1A1 | |
| SCHEMBL23130617 | 0.84 | HTR2C (0.52) | HTR2CCHRM1LMNATSHRALDH1A1 | |
| SCHEMBL29284130 | 0.81 | HTR2C (0.50) | HTR2CLMNATSHRPOLBSMN1; SMN2 | |
| SCHEMBL21871359 | 0.80 | HTR2C (0.52) | HTR2CCHRM1CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL21847086 | 0.79 | HTR2C (0.51) | HTR2CCHRM1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL21358349 | 0.78 | CHRM1 (0.46) | HTR2CCHRM1GAA | |
| SCHEMBL4680881 | 0.78 | HTR2C (0.77) | HTR2CALDH1A1 | |
| SCHEMBL4680887 | 0.78 | HTR2C (0.77) | HTR2CALDH1A1 | |
| SCHEMBL13321596 | 0.78 | CHRM1 (0.55) | CHRM1GAAKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138566-A | Piperazinyl cyclobutenones | G. D. SEARLE & CO. (US) | 1979-02-06 | — | — | US | disclosed |