Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23130617 | 1.00 | HTR2C (0.52) | HTR2CLMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL29284130 | 0.94 | HTR2C (0.50) | HTR2CLMNAPOLBSMN1; SMN2GBA2 | |
| SCHEMBL28877769 | 0.84 | LMNA (0.47) | HTR2CLMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL11533237 | 0.84 | HTR2C (0.59) | HTR2CLMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL11533240 | 0.84 | HTR2C (0.59) | HTR2CLMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL31692676 | 0.82 | LMNA (0.43) | HTR2CLMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL21219897 | 0.82 | LMNA (0.43) | HTR2CLMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL30387113 | 0.82 | LMNA (0.43) | HTR2CLMNAPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL21712561 | 0.81 | SMN1; SMN2 (0.45) | LMNAPOLBSMN1; SMN2ALDH1A1ATM | |
| SCHEMBL31612922 | 0.79 | LMNA (0.43) | HTR2CLMNAPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054512-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |