Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537297 | 0.85 | ALKBH5 (0.49) | ALKBH5TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL11532835 | 0.85 | TSHR (0.41) | ALKBH5TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL11530445 | 0.85 | TSHR (0.41) | ALKBH5TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL11526833 | 0.85 | ALKBH5 (0.52) | ALKBH5TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL11534268 | 0.85 | MAPT (0.45) | ALKBH5TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL11296133 | 0.85 | TSHR (0.56) | ALKBH5TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL11533850 | 0.82 | KDM4C (0.38) | ALKBH5MMEALDH1A1KMT2AMEN1 | |
| SCHEMBL11537033 | 0.82 | MAPT (0.57) | ALKBH5TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL11532160 | 0.81 | MAPT (0.52) | ALKBH5TSHRKMT2AMEN1HTT | |
| SCHEMBL11570188 | 0.79 | TSHR (0.44) | ALKBH5TSHRALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141890-A | FIBER-REACTIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |