Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1347394 | 0.90 | KMT2A (0.54) | LMNAKMT2AALDH1A1MEN1CYP1A2 | |
| SCHEMBL11531880 | 0.88 | KMT2A (0.47) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL11533194 | 0.88 | KMT2A (0.54) | KMT2ACYP11B1CYP11B2ALDH1A1MEN1 | |
| SCHEMBL11533715 | 0.86 | KMT2A (0.53) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL11537324 | 0.81 | KMT2A (0.48) | RAB9AKMT2AMEN1USP2 | |
| SCHEMBL11531936 | 0.80 | MEN1 (0.48) | LMNAKMT2AALDH1A1MEN1CYP1A2 | |
| SCHEMBL6544989 | 0.80 | KMT2A (0.50) | RAB9AKMT2AALDH1A1MEN1USP2 | |
| SCHEMBL11533042 | 0.79 | KMT2A (0.46) | RAB9ALMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL11531498 | 0.77 | USP2 (0.41) | RAB9AKMT2AUSP2HSP90AA1 | |
| SCHEMBL17810214 | 0.76 | HSD17B10 (0.48) | RAB9AKMT2ACYP11B1CYP11B2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | disclosed |